Signaling Response Prediction (DREAM3, Challenge 2)

Synopsis

Approximately 10,000 intracellular measurements (fluorescence signals proportional to the concentrations of phosphorylated proteins) and extracellular measurements (concentrations of cytokines released in response to cell stimulation) were acquired in human normal hepatocytes and the hepatocellular carcinoma cell line HepG2 cells. The datasets consist of measurements of 17 phospho-proteins (at 0 min, 30 min, and 3 hrs) and 20 cytokines (at 0 min, 3 hrs, and 24 hrs) in two cell types (normal and cancer) after perturbations to the pathway induced by the combinatorial treatment of 7 stimuli and 7 selective inhibitors.

About the Data

Data generously provided by Peter Sorger, Harvard Medical School / MIT

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Retrieved from "http://wiki.c2b2.columbia.edu/dream/index.php/D3c2"

This page has been accessed 7,269 times. This page was last modified 05:38, 23 November 2009.

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