Software:EDGI General Description

From Honiglab_public

EDGI (Enhancer Detection using only Genomic Information) integrates a traditional motif-discovery algorithm SPLASH with a novel local permutation-clustering algorithm PromoClust in order to identify large regulatory elements (e.g. enhancers) as evolutionarily conserved, order-independent clusters of short conserved motifs. EDGI relies on the evolutionary conservation of the binding sites for regulating transcription factors, without requiring knowledge of these transcription factors or their binding sites.