Software:PUDGE General Description
Computational protein structure prediction using sequence homology is a process that exploits the observation that proteins with similar sequences usually have similar structures as well. While this idea is simple in theory, in practice, the process of using sequence homology to predict protein structure is intricate and complex. The process is generally divided into five stages, involving the use of a combination of techniques from a variety of scientific disciplines. See Petrey & Honig, 2005 for a description of the overall protein structure prediction process.
PUDGE is supported by a funding from the NIH Grant # GM030518, NESG NIH Grant # GM074958 and MAGNet NIH Grant # CA121852
Developed in the Honig Lab