Software:SPIN-PP

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SPIN-PP

Surface Properties of INterfaces - Protein Protein Interfaces

SPIN-PP is a database of all protein-protein interfaces present in the PDB. The program GRASP was used to create molecular surfaces of each half of all 2-chain complexes present in the PDB. A basic set of physico-chemical properties were then mapped on to these surfaces, which were then used to classify the interfaces into a surface property taxonomy. The mapped properties currently include surface curvature, electrostatic potential, based on formal charges, sequence variability, based on the HSSP alignments, and hydrophobicity, on an atom-based model.


Address SPIN-PP related questions to:
  • spin<at>flash62.bioc.columbia.edu



SPIN-PP is supported by a funding from the National Science Foundation Grant # DBI-9904841

Developed in the Honig Lab

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