Regulatory network reconstructed using the ARACNe algorithm. Nodes represent genes and edges represent ARACNe-predicted interactions between transcription factors and their putative targets. The results of a prior differential expression analysis have been overlaid on the network and are shown as red and blue colored nodes (representing over- or under-expressed genes. Transcription factors whose set of predicted targets are enriched in differentially expressed genes are potentially involved in the regulation of the molecular program that implements the differential phenotype.