Fold Change - Revision history

Smith: /* Overview */

2015-03-13T20:31:43Z

‎Overview

2012-05-11T14:23:30Z

‎References

2012-05-11T14:23:20Z

‎References

2012-05-11T14:23:03Z

‎References

2012-05-11T14:22:02Z

‎References

2012-05-11T14:21:51Z

2012-03-01T23:09:59Z

‎Setup

2012-03-01T23:08:35Z

‎Setup

2012-03-01T23:07:48Z

‎Setup

2012-02-29T00:03:06Z

‎Ratio

← Older revision		Revision as of 20:31, 13 March 2015
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	Two methods are provided to calculate fold change. The component also allows either calculation to be carried out starting with either linear or log2-transformed data.		Two methods are provided to calculate fold change. The component also allows either calculation to be carried out starting with either linear or log2-transformed data.
		+
		+
		+	'''Note''' - Despite the flexibility offered by this component, the most relevant calculation for log2 transformed input data is the "Difference of average log2 values".

	[[Image:Fold_Change_Analysis.png]]		[[Image:Fold_Change_Analysis.png]]

← Older revision		Revision as of 14:23, 11 May 2012
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	==References==		==References==

−	A comparison of fold-change and the t-statistic for microarray data analysis (2007) Witten and Tibshirani [http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf \| link to paper].	+	A comparison of fold-change and the t-statistic for microarray data analysis (2007) Witten and Tibshirani [http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf link to paper].

← Older revision		Revision as of 14:23, 11 May 2012
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	==References==		==References==

−	A comparison of fold-change and the t-statistic for microarray data analysis (2007) Witten and Tibshirani[[http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf \| link to paper].	+	A comparison of fold-change and the t-statistic for microarray data analysis (2007) Witten and Tibshirani [http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf \| link to paper].

← Older revision		Revision as of 14:23, 11 May 2012
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	==References==		==References==

−	~~[http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf~~ A comparison of fold-change and the t-statistic	+	A comparison of fold-change and the t-statistic for microarray data analysis (2007) Witten and Tibshirani[[http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf \| link to paper].
−	for microarray data analysis (2007) Witten and Tibshirani].

← Older revision		Revision as of 14:22, 11 May 2012
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	[http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf A comparison of fold-change and the t-statistic		[http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf A comparison of fold-change and the t-statistic
−	for microarray data analysis (2007) Witten and Tibshirani.	+	for microarray data analysis (2007) Witten and Tibshirani].

← Older revision		Revision as of 14:21, 11 May 2012
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	[[Image:Fold_Change_Analysis_Result.png]]		[[Image:Fold_Change_Analysis_Result.png]]
		+
		+	==References==
		+
		+	[http://www-stat.stanford.edu/~tibs/ftp/FCTComparison.pdf A comparison of fold-change and the t-statistic
		+	for microarray data analysis (2007) Witten and Tibshirani.

← Older revision		Revision as of 23:09, 1 March 2012
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−	[[Image:~~Fold_Change_Analysis~~.png]]	+	[[Image:Fold_Change_Analysis_Settings.png]]

	===Results===		===Results===

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 ===Setup===
 * At least two set of markers must be activated, and at least one marked as Case and one marked as Control.
 [[Image:Fold_Change_Analysis_Arrays.png]]
 ===Results===

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 * For each marker, calculate Avg(Case arrays) / Avg(Control arrays).
 * Ratios less than 1 are inverted and given a negative sign, e.g. 0.25 is reported as -4.
 ====Difference of average log2 values====
 * Calculated with log2 values.  Linear data will be transformed to log2 (shown in formula below).