GSEA

Revision as of 15:56, 14 January 2014 by Smith (talk | contribs) (References)

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Overview

Coming soon!

Prerequisites

  • An expression dataset must be loaded in the Workspace.
  • Two (and only two) array sets must be activated in the Arrays component. They do not need to be marked "Case" or "Control", this will have no effect. These sets define the two classes used to calculate a measure of differential expression and from that the rank order of genes.

Parameters

Required Parameters

GSEA Required Parameters.png

Basic Parameters

GSEA Basic Parameters.png


Advanced Parameters

GSEA Advanced Parameters.png


Results

GSEA Results Report.png


GSEA Enrichment Results Snapshot.png


GSEA Heatmap.png

References

  • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 102(43):15545-50. PubMed 16199517
  • GenePattern modules documentation.