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  • What labs and/or how many are using PROSITE?

    20 C2B2/MAGNet labs and about 50 Cancer-center and non-cancercenter labs

  • Who is the main “database authority” for PROSITE?

    Richard Friedman (friedman<at>

  • What kind of database is it? (flat-file, relational, XML, etc)


  • Size of database?

    1,300 patterns

  • Anticipated yearly growth? (Megabytes/Gigabytes)

    can't predict

  • Backup procedures? How often?
    • Database backups (Hot, Cold, Both) [and/or]
    • Operating system backup

      OS backup

  • What servers/operating systems are hosting them (IP addresses)
  • Approximately how many *active* users?
  • 200

  • How often is the database used? (Daily, Weekly, Monthly)


  • What platforms are being used? (Oracle, MySQL, PostgreSQL, etc)


  • What applications are using these databases?
    • Web interface?
    • Application (GUI)?
    • Command line interface (CUI)?
    • Command line (GCG package) and x-Windows (seqlab)
  • Is it accessible from outside the firewall to public users?


  • What is the primary purpose of the database & types of data stored?
    • PROSITE currently consists of a large collection of biologically meaningful motifs that are described as patterns or profiles, and linked to documentation briefly describing the protein family or domain they are designed to detect.
    • The close relationship of PROSITE with the SWISS-PROT protein database allows the evaluation of the sensitivity and specificity of the PROSITE motifs and their periodic reviewing.
    • It is useful for the identification of functional and structural motifs in protein sequences.
  • May I access the database and if so, what is the login info?
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