User:Bjagla
Contents
- 1 Feature requests for geWorkbench
- 1.1 General Features
- 1.2 Programmatic features
- 1.3 Menu
- 1.4 Project Folders
- 1.5 Markers
- 1.6 Arrays/Phenotypes
- 1.7 Sets
- 1.8 FASTA sequences
- 1.9 Microarray data
- 1.9.1 Simulation
- 1.9.2 Network browser
- 1.9.3 Interactions
- 1.9.4 Aracne
- 1.9.5 Tabular Microarray Viewer
- 1.9.6 Sequence Retriever
- 1.9.7 Synteny
- 1.9.8 Microarray viewer
- 1.9.9 Gene Ontology
- 1.9.10 GSEA
- 1.9.11 Reverser Engineering
- 1.9.12 Scatter Plot
- 1.9.13 caBIO pathways
- 1.9.14 Marker Annotations
- 1.9.15 Color Mosaic Expression Profiles
- 1.9.16 Expression Value Distribution
- 1.9.17 Experiment Info
- 1.9.18 Synteny Parameters
- 1.9.19 Normalization
- 1.9.20 T-Profiler
- 1.9.21 Analysis
- 1.9.22 Associations
- 1.9.23 caScript
- 1.9.24 Dataset Annotations
- 1.9.25 Filtering
- 1.9.26 Dataset History
Feature requests for geWorkbench
General Features
- Not in Mantis:
There are problems related to memory management. geWorkbench uses too much memory for storing Microarray data internally. When loading 9 U133 chips one needs more than 512MB.
- Mantis 0000114: Persisting configuration settings designated through the visual builder
At present, changes to the start up configuration effected during the application execution (through the Visual Builder) do not get persisted: when the application is launched the original start up configuration is used again.
It is desirable that changes introduced by the Visual Builder be persisted in the application's configuration file so that they can be "remembered" at the next launch.
- Mantis 0000115: Choosing among available application "flavors"
During application launch, a start up window (which the user can opt to hide for subsequent application invocations) should prompt the user to select one among the available application configuration "flavors". This functionality should be available not only at start up but also from within the application, through a "Preferences" type of menu option.
- Mantis 0000077: Context sensitive online help
We need to make online help available in a context sensitive manner: from within a component, a user should be able (using F1 or by pressing a Help button) get access to the online help associated with the component.
- Mantis 0000156: Extension of event exchange model
Entering this here as a placeholder regarding the proposed re-engineering of the event model. Some of the design suggestions that have been mentioned include:- Making it a rule that event data are always interfaces.
- Removing the need to specify within the throwEvent() method the listener interface and the method to invoke in that interface.
- Using annotations (or some other mechanism) in order to provide a direct reference to a service provider so that methods can be invoked directly rather than through event exchanges.
- Mantis 0000157: Extend framework to bring to focus components that receive appropriate events
An issue with the GUI is that one needs to know which components respond to which events in order to inspect the results of some action. E.g., when executing the hierarchical clustering analysis and in order to review the results one needs to explicitly select the Dendrogram tab.
The framework needs to be extended so that components can gain the focus as appropriate when they receive certain events.
- Mantis 0000173: UI Tab Display.
Tabs should be displayed in alphabetical order. It's difficult to find tabs as they are ordered currently.
If the user cannot view all the tabs without scrolling, the tab headers should become drop down values.
Programmatic features
- Mantis 0000400: Inconsistent t-test results based on phenotype/panel activation order
There should have been no significant genes found once the marker selection had been made but the volcano plot was erroneously displaying the genes that had been selected as being significant. This is due to an inconsistency in the way the markers() method is implemented in CSMicroarraySetView. For the time being I've routed around this method but it should probably be changed at some point.
Menu
- Mantis 0000166: main menubar controls for Project Folders Area are confusing.
The problem is caused by the differences in type and semantics between workspace folder and project folders. For example, The "File" submenu offers "Open" and the pop-up choices are "File" or "Workspace". Select Workspace and you are offered a dialog box. Select "File" and you are told you must first select a project node. Or if you select "New" (an adjective) from the submenu, you get a choice of "Workspace" or "Project". Select "Workspace" and the current workspace folder is cleared of its contents. Thus New Workspace actually REMOVES the Workspace folder, whereas the submenu item "Remove" does not include "workspace" as an option. Select "Project" and a new project folder is added without replacing an existing one. I think the whole thing could be made more obvious and logical by making the File submenu items "Workspace" and "Projects" and perhaps "Files". Then the choices under each could be actions (verbs) - e.g Open, Remove, Load, Delete, Save, etc. In other words, you consider the folder that you want to do something to, select it in the file menu and choose the action that you want to take. Also the other file items "Export" etc. have nothing to do with the Project Folders Area and are positioned awkwardly.
File
- Mantis 0000345: File Loading Confusion
No choice to list all files in directory. The file selection box should contain an option to see all the files in a directory, otherwise unclear which file postfix goes with which loading option.
- Mantis 0000347: Prompt to Save
No prompt to save workspace when application exits, there should also be a way to exit the application from the file menu.
Edit
View
Commands
Tools
Help
Project Folders
Markers
Arrays/Phenotypes
Sets
- Mantis 0000381: Renaming a label erases its class (case, control, etc.) status.
Renaming a label erases its class (case, control, etc.) status. To reproduce, set a label's class to 'case', then rename that label.
FASTA sequences
Promoter
Sequence Panel
Position Histogram
Simulation
Network Generator
Phenotype & Optimizer Options
Interactions Display
5. Sequence alignment
BLAST
- related to 0000541: blastall is not complete
using local / own databases
HMM
Other
Pattern discovery
Associations
caScript
Dataset annotations
data history
Experiment Info
Microarray data
The following panels/functionalities are requested specifically for Microarray data:
Simulation
Network browser
Interactions
Aracne
Tabular Microarray Viewer
Sequence Retriever
Synteny
Microarray viewer
- related to (closed) Mantis 0000225: Microarray panel details
It would be nice to have the values (min, max) displayed next to the color legend
Gene Ontology
GSEA
Reverser Engineering
Scatter Plot
caBIO pathways
Marker Annotations
Color Mosaic Expression Profiles
Expression Value Distribution
Experiment Info
Synteny Parameters
Program
MUMmer
Dots
Synteny map
Genome selections
Annotations
Normalization
Housekeeping Genes Normalizer
Log2 Transformation
Marker-based centering
Mean-variance normalizer
Array-based centering
Missing value computations
Threshold Normalizer
Quantile Normalization
T-Profiler
Analysis
The following analysis functions are requested:
- ANOVA
Fast Hierarchical clustering
- Mantis 0000148: Euclidean distance shoud use normalized vectors
Data should be transiently normalized
Matrix reduce
Svm classifier
Slmr classifier
SOM
T-test
Multi T-test
Associations
caScript
Dataset Annotations
Filtering
Deviation filter
Affy detection call filter
Expression threshold filter
Genepix flags filter
Missing value filter
2 channel threshold filter
Dataset History
- Mantis: 0000300: need array info
We should be able to display information about a microarray - the chip type, the number of markers in the dataset vs in the chip definition.