Marker Annotations

Revision as of 17:27, 14 July 2006 by Smith (talk | contribs) (Retrieving selected annotations)

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For this tutorial, we will examine the group of markers selected in an excercise similar to that shown in the Hierarchical Clustering tutorial. geWorkbench can retrieve gene and pathway information from databases hosted at the NCI.

Retrieving selected annotations

1. We will assume you have already created a set of markers of interest in the "Marker Sets" component, for example through performing Hierarchical Clustering and saving a set of markers.

2. The desired marker set should be activated by checking its box in the Marker Sets component. Here is an example taken from the Hierarchical Clustering tutorial:

T Markers ClusterTree12and44.png

3. In the Marker Annotations component, select Retrieve Annotations.


T MarkerAnnotations ClusterTree.png

Displaying annotations and pathway diagrams

The links under the heading Gene can be clicked to display information from the CGAP database at the NCI:


T CGAP Page for NME1.png


The Pathway links can be clicked to display BioCarta pathway diagrams provided through the NCI's caCORE/caBIO resource. The graphical components are themselves clickable to provide further information.


T caBIO Pathways h ndkDynamin.png