Fold Change
Overview
(The Fold Change component was inadvertently omitted from geWorkbench release 2.2.0. It is available in the development version).
Fold change is used to compare the expression of genes between two sets of arrays, e.g. case and control sets.
This component allows a threshold for fold-change to be set. Markers that exceed the threshold are placed into new sets in the Markers component - one for those with positive fold-change, the other for negative (where the inverse is above threshold).
Two methods are provided to calculate fold change. The component also allows either calculation to be carried out starting with either linear or log2-transformed data.