Difference between revisions of "BISON"
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+ | __NOEDITSECTION__ | ||
+ | {{TutorialsTopNav}} | ||
+ | |||
+ | The tutorials shown on this page provide a quick introduction to the most important features of geWorkbench. Additional information can be found in the User Guide (in preparation) and in the Online Help section of the program. | ||
+ | |||
+ | All data sets used in the tutorials are available from the [[Download#Tutorial_data | download area]] of our site. | ||
+ | |||
+ | |||
+ | |||
+ | ===[[Tutorial - Getting_Started | Getting Started]]=== | ||
+ | Obtaining and installing geWorkbench. Requirements. | ||
+ | |||
+ | ===[[Tutorial - Basics | Basics]]=== | ||
+ | A brief introduction to the use of geWorkbench. | ||
+ | |||
+ | ===[[Tutorial - Projects and Data Files | Projects and Data Files]]=== | ||
+ | Creating projects, loading microarray data files, merging into one dataset, and saving. | ||
+ | |||
+ | ===[[Tutorial - Project Details | Project Details]]=== | ||
+ | Creating projects, loading microarray data files, merging into one dataset, and saving. | ||
+ | |||
+ | ===[[Tutorial - Data Subsets | Data Subsets]]=== | ||
+ | Subsets of both markers and arrays can be defined for targeted analysis. | ||
+ | |||
+ | ===[[Tutorial - Viewing a Microarray Dataset | Viewing a Microarray Dataset]]=== | ||
+ | Survey of geWorkbench visusaliztion tools for microarray data. | ||
+ | |||
+ | ===[[Tutorial - Filtering and Normalizing | Filtering and Normalizing]]=== | ||
+ | geWorkbench provides numerous methods for filtering and normalizing microarray data. | ||
+ | |||
+ | ===[[Tutorial - EVD | Expression Value Distribution]]=== | ||
+ | View and manipulate a histogram of the distribution of expression values for each array. | ||
+ | |||
+ | ===[[Tutorial - Differential Expression | Differential Expression]]=== | ||
+ | Several variants of the t-test are available. | ||
+ | |||
+ | ===[[Tutorial - Clustering | Clustering]]=== | ||
+ | Data can be clustered using a fast hierarchical clustering routine, as well as SOMs. | ||
+ | |||
+ | ===[[Tutorial - Marker Annotations | Marker Annotations]]=== | ||
+ | Marker annotations can be retrieved, including BioCarta pathway diagrams. | ||
+ | |||
+ | ===[[Tutorial - Sequence Retrieval | Sequence Retrieval]]=== | ||
+ | Genomic sequences for markers can be retrieved for further analysis. | ||
+ | |||
+ | ===[[Tutorial - BLAST | BLAST]]=== | ||
+ | geWorkbench can run BLAST jobs on the JCSB cluster. | ||
+ | |||
+ | ===[[Tutorial - Pattern Discovery | Pattern Discovery]]=== | ||
+ | Upstream seqeunce can be analyzed for conserved sequence patterns. | ||
+ | |||
+ | ===[[Tutorial - Promoter Analysis | Promoter Analysis]]=== | ||
+ | Search a set of sequences against a promoter database. | ||
+ | |||
+ | ===[[Tutorial - Reverse Engineering | Reverse Engineering]]=== | ||
+ | Simple network reverse engineering - microarray datasets can be analyzed for interactions between genes. | ||
+ | |||
+ | ===[[Tutorial - ARACNE | ARACNE]]=== | ||
+ | Formal method for reverse Engineering - microarray datasets can be analyzed for interactions between genes. | ||
+ | |||
+ | ===[[Tutorial - Network Browser| Network Browser]]=== | ||
+ | Provides visualization of adjacency matrix generated by ARACNE, using Cytoscape. | ||
+ | |||
+ | ===[[Tutorial - GO Term Enrichment | GO Term Enrichment]]=== | ||
+ | Determine if particluar Gene Ontology terms are overrepresented in a data subset. | ||
+ | |||
+ | ===[[Tutorial - Synteny | Synteny]]=== | ||
+ | Compare genomic sequence from two different species. | ||
+ | |||
+ | ===[[Tutorial - Jmol | Jmol]]=== | ||
+ | Jmol is a molecular structure viewer for viewing PDB format files. |
Revision as of 13:10, 13 February 2007
The tutorials shown on this page provide a quick introduction to the most important features of geWorkbench. Additional information can be found in the User Guide (in preparation) and in the Online Help section of the program.
All data sets used in the tutorials are available from the download area of our site.
Contents
- 1 Getting Started
- 2 Basics
- 3 Projects and Data Files
- 4 Project Details
- 5 Data Subsets
- 6 Viewing a Microarray Dataset
- 7 Filtering and Normalizing
- 8 Expression Value Distribution
- 9 Differential Expression
- 10 Clustering
- 11 Marker Annotations
- 12 Sequence Retrieval
- 13 BLAST
- 14 Pattern Discovery
- 15 Promoter Analysis
- 16 Reverse Engineering
- 17 ARACNE
- 18 Network Browser
- 19 GO Term Enrichment
- 20 Synteny
- 21 Jmol
Getting Started
Obtaining and installing geWorkbench. Requirements.
Basics
A brief introduction to the use of geWorkbench.
Projects and Data Files
Creating projects, loading microarray data files, merging into one dataset, and saving.
Project Details
Creating projects, loading microarray data files, merging into one dataset, and saving.
Data Subsets
Subsets of both markers and arrays can be defined for targeted analysis.
Viewing a Microarray Dataset
Survey of geWorkbench visusaliztion tools for microarray data.
Filtering and Normalizing
geWorkbench provides numerous methods for filtering and normalizing microarray data.
Expression Value Distribution
View and manipulate a histogram of the distribution of expression values for each array.
Differential Expression
Several variants of the t-test are available.
Clustering
Data can be clustered using a fast hierarchical clustering routine, as well as SOMs.
Marker Annotations
Marker annotations can be retrieved, including BioCarta pathway diagrams.
Sequence Retrieval
Genomic sequences for markers can be retrieved for further analysis.
BLAST
geWorkbench can run BLAST jobs on the JCSB cluster.
Pattern Discovery
Upstream seqeunce can be analyzed for conserved sequence patterns.
Promoter Analysis
Search a set of sequences against a promoter database.
Reverse Engineering
Simple network reverse engineering - microarray datasets can be analyzed for interactions between genes.
ARACNE
Formal method for reverse Engineering - microarray datasets can be analyzed for interactions between genes.
Network Browser
Provides visualization of adjacency matrix generated by ARACNE, using Cytoscape.
GO Term Enrichment
Determine if particluar Gene Ontology terms are overrepresented in a data subset.
Synteny
Compare genomic sequence from two different species.
Jmol
Jmol is a molecular structure viewer for viewing PDB format files.